Molecular localization of cold compounds
-
No requirement for specialized radioactive compound management, storage, equipment, permits, or specializedemployees
-
Imaging the molecules after scaled syntheses thus incorporates costs for brain localization studies already in functioning costs of scale-up and stability studies
-
No alternative synthesis routes required to incorporate radio-labels or heavy metals in the clinical candidates
- Extended shelf life of the cold compounds
- Safe: the lack of non-ionizing agents signifies that even volatile compounds, such as anesthetics, can be studied safely
- Non-invasive imaging modality without surgical procedures
-
Animals can be reused or retested on short time cycles
- Fast and specific to the compound atomic composition
-
Time courses of compound brain localization obtainable
Added value
-
Proof in concept for brain exposure of new molecular types
- Pre-filtering for clinical candidate selection
-
Applicable to rational drug design
Risk evaluation for imaging with ionizing agents
- More information = better decision
-
Never randomly select compounds for radio-labeled biobiodistribution studies again!
Use left/right arrows to navigate the slideshow or swipe left/right if using a mobile device
